The development of chromosomal abnormalities after diagnosis may have a negative impact on prognosis for myelodysplastic syndromes (MDS) patients according to a recent study published in the Annals of Hematology.
Italian researchers found that patients who developed misshapen chromosomes after diagnosis in a process called cytogenetic evolution had a 7 times higher risk of shorter survival and a 36 times higher risk of progressing to acute myeloid leukemia (AML) than chromosomally stable patients.
The study revealed that 30.7 percent of…
The treatment options for myelodysplastic syndromes (MDS) patients represents a continuing discovery process with different levels of intensity as evaluated in a recent review of treatment options published in the supplement of the journal Cancer Control.
The main goals when treating high-risk MDS patients are to increase overall survival and delay progression to acute myeloid leukemia (AML). Researchers also strive to improve quality of life through supportive care, achieve independence from red blood cell transfusions, and decrease symptoms.
Options for…
Myelodysplastic syndromes (MDS) patients with skin lesions may have a slightly higher chance of disease progression to acute myeloid leukemia (AML) according to a recent study conducted by French researchers.
The study authors pointed out that although the risk of AML transformation was higher for patients with skin lesions, it was not a significant vulnerability. They suggested dermatologists work closely with hematologists to assess skin conditions in patients with MDS.
Skin lesions differ by diagnosis but are usually characterized by…
A high lymphocyte count at diagnosis may predict longer survival time for myelodysplastic syndromes (MDS) patients, according to a recent study published in the American Journal of Hematology.
Lymphocytes are a type of white blood cell that defend the body against infections and play a vital role in the body’s immune response. Lymphocyte count is a frequently used prognostic indicator in lymphoid cancers.
Previous research has shown that immune system may be linked to the development of MDS (see related…