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Study Shows Iron Chelating Properties Of Wheat Grass Juice (ASCO 2009)

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Published: Jun 2, 2009 2:38 pm
Study Shows Iron Chelating Properties Of Wheat Grass Juice (ASCO 2009)

Researchers from India presented a study examining the effects of wheat grass juice as an iron chelator in transfusion-dependent myelodysplastic syndromes (MDS) patients on May 29 at the 2009 American Society of Clinical Oncology (ASCO) meeting.

Patients with MDS or other transfusion-dependent diseases are at risk for toxic iron build-up in cells, and possible organ damage. Iron chelators bind to excess iron for removal from the body.

The study included 20 transfusion-dependent MDS patients between the ages of 42 of 72 years (median 55 years). The participants drank 30 mL of fresh wheat grass juice daily for six months. Blood ferritin levels were, on average, reduced from 2,250 to 950 ng/mL. Ferritin, an iron-storage protein that prevents iron from forming free radicals, corresponds to blood iron levels and ranges from 12 to 300 ng/mL in healthy adult males and 12 to 150 ng/mL in females.

In addition, blood transfusion intervals lengthened and performance status of patients increased from 60 to 80 percent.

This trial followed a study with 200 intermediate thalassemia, or major chronic anemia, patients in which 80 percent who drank wheat grass juice became transfusion-independent.

In a dose-dependent comparison with deferoxamine (Desferal), a standard iron chelator, soluble wheat grass extract, collected from five to seven day old leaves, showed more effective iron chelating ability. In addition, analysis by a separation technique showed the crude extract to be rich in oxalic and malic acid, which possibly function in the dietary absorption of iron from the intestine.

Researchers encourage the use of wheat grass juice for patients requiring repeated blood transfusions.

For more information, please see abstract 7012 at the 2009 ASCO meeting Web site.

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5 Comments »

  • Margarete Aulehla said:

    “This trial followed a study with 200 intermediate thalassemia, or major chronic anemia, patients in which 80 percent who drank wheat grass juice became transfusion-independent.”

    Where can i read/get this study?

    “In a dose-dependent comparison with deferoxamine (Desferal), a standard iron chelator, soluble wheat grass extract, collected from five to seven day old leaves, showed more effective iron chelating ability.”

    Is this another study, and if yes: Would it be possible to get it?

    Thank you, M. Aulehla

  • Margarete Aulehla said:

    Finally i found the studies:

    1. The Role of Iron Chelation Activity of Wheat Grass Juice in Blood Transfusion Requirement of Intermediate Thalassaemia, 2007.

    http://abstracts.hematologylibrary.org/cgi/content/abstract/110/11/3829
    Wheat grass could be an effetive alternative to transfusions

    2. Soma Mukhopadhyay, PhD in her presentation of the study in this article gives more informations

    Here you find the slides

    http://www.asco.org/ASCOv2/MultiMedia/Virtual+Meeting?&vmview=vm_session_presentations_view&confID=65&sessionID=395

  • michelle hand said:

    Ihave recently descovered the iorn chelation properities of wheat grass. I have commenced a pt on wheat grass for iorn overload (MDS pt) I am just enquiring what doesage is required to be administered for best results? If Icould be advised on the above I would be very grateful.
    kind regards
    michelle

  • MDS Beacon Staff said:

    Dear Michelle,

    The abstract for the study says the following:

    The fresh leaves of 5-7-day-old wheat grass, including stems, were made into fresh juice. 30 mL of juice were given daily continuously for 6 months.

  • Margarete Aulehla said:

    http://www.asco.org/ascov2/Meetings/Abstracts?&vmview=abst_detail_view&confID=65&abstractID=33788

    Look into presentation Nr. 1 (scroll down to the bottom of the abstract page: In slide 7 a study-quantity of 30 ml of juice 2 – 3 times a day is indicated. But this is no pure juice (in aqueous solution). 30 ml are produced from 5 grams of fresh wheat grass.