[ by | Dec 7, 2011 2:10 pm | No Comment ]
Latest MDS Research Findings To Be Presented At The American Society Of Hematology Annual Meeting (ASH 2011)

The American Society of Hematology will hold its 53rd annual meeting this Saturday, December 10, through Tuesday, December 13, in San Diego.

Medical professionals will gather during the four-day meeting to discuss the latest findings for various blood diseases, including myelodysplastic syndromes (MDS).

The American Society of Hematology (ASH) meeting includes education and scientific sessions, poster viewings, and oral presentations, as well as meet-the-expert opportunities.

The latest MDS research findings will be discussed in over 50 oral presentations and more than 170 posters. In addition, the meeting features six education…

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[ by | Dec 1, 2011 7:57 am | 7 Comments ]
“Myelodysplastic Syndromes” — What’s In The Name? Part 1: History

In this edition of his quarterly column for The MDS Beacon, Dr. Steensma answers the question, “Where does the name myelodysplastic syndromes come from?” The column will be published as a two-part series. In Part 1, Dr. Steensma describes the history of the disease name. In Part 2, he will address the origins of the name.

Although every English-speaking adult has heard the word “leukemia” and most people have at least some sense what sort of disease leukemia represents, the term “myelodysplastic syndromes” (MDS) is not widely…

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[ by | Nov 29, 2011 12:52 pm | No Comment ]
Vidaza-Revlimid Combination Shows Promise For Higher-Risk MDS Patients With Chromosomal Abnormalities

Results of a small French study suggest that the use of Vidaza and Revlimid as a first-line therapy in higher-risk myelodysplastic syndromes patients with several chromosomal abnormalities is effective and tolerable.

The most common side effects were low blood cell counts, which required close monitoring. However, the study authors concluded from these results that the side effects were acceptable when compared to conventional chemotherapy, which is often ineffective and intolerable in high-risk patients.

Previous research has shown that the combination therapy of Vidaza (azacitidine) and Revlimid (lenalidomide) is…

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[ by | Nov 22, 2011 3:29 pm | No Comment ]
Selective Screening Before Immunosuppressive Therapy Improves Response Rates In MDS Patients

Results of a recent Chinese study suggest that a new set of criteria for selecting myelodysplastic syndromes patients for immunosuppressive therapy can improve treatment response rates and reduce the share of patients progressing to leukemia.

The study authors found that treatment response rates in their trial were directly associated with the number of screening criteria patients met. For patients who met all screening criteria, 100 percent responded to therapy.

In myelodysplastic syndromes (MDS), the bone marrow produces an excess of developing blood cells that are unable to properly mature and function.…

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[ by | Nov 17, 2011 2:36 pm | No Comment ]
Low Ferritin Levels Associated With Better Prognosis After Stem Cell Transplantation

New research from Japan indicates that low levels of the blood protein ferritin are associated with better outcomes in myelodysplastic syndromes (MDS) patients who undergo stem cell transplantation.

“In both [standard- and high-risk] MDS, elevated ferritin has a negative effect on the outcomes of transplantation,” said study author Dr. Takayoshi Tachibana of the Yokohama City University Medical Center in Yokohama, Japan.

Dr. Tachibana pointed out that patients with elevated ferritin levels should nevertheless undergo stem cell transplantation because “We think transplantation is the most promising therapy [for MDS patients].”

Instead…

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